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A Framework for Cross-Domain Generalization in Coronary Artery Calcium Scoring Across Gated and Non-Gated Computed Tomography

Mahmut S. Gokmen, Moneera N. Haque, Steve W. Leung, Caroline N. Leach, Seth Parker, Stephen B. Hobbs, Vincent L. Sorrell, W. Brent Seales, V. K. Cody Bumgardner

Details

Journal arXiv preprint
Year 2026
Categories cs.CV, cs.AI

Abstract

Coronary artery calcium (CAC) scoring is a key predictor of cardiovascular risk, but it relies on ECG-gated CT scans, restricting its use to specialized cardiac imaging settings. We introduce an automated framework for CAC detection and lesion-specific Agatston scoring that operates across both gated and non-gated CT scans. At its core is CARD-ViT, a self-supervised Vision Transformer trained exclusively on non-gated data using the DINOv2 architecture with register tokens.