Open Science Initiative

Kentucky Open Science

A statewide hub that connects people who have research challenges with the data, models, and computing to address them, and makes every resource in the Commonwealth usable from one place.

Search the hub

Ask a question in plain language, or search models, datasets, projects, people, and publications.

How the hub works

Define a challenge once. The hub keeps working on it.

Agents keep evaluating new methods against each challenge, PanAtlas links what they find, and the people working on related challenges are brought together.

The hub's six steps, run by Astral agents. 1, define and encode: a participant or group defines a challenge (question, data, success, rules) and agents encode it as a specification. 2, discover and evaluate: new papers, techniques, and models are evaluated against every recorded challenge across language, vision, audio, time series, and tabular methods. 3, link and cluster: PanAtlas links records to Wikipedia and curated ontologies and joins data, models, and evaluations into clusters. 4, convene: new teams and working groups form where clusters of interest appear. 5, advance: the field advances, agents find new methods, and teams take them up. 6, inform: automated and interactive agent updates, and the cycle repeats.

Projects

Applied research projects across healthcare, agriculture, public health, and education.

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smell-datasets

Project

smell-datasets Unless otherwise noted, this work is derived from the Institute for Biomedical Informatics Innovation Core at the University of Kentucky. Introduction Electronic nose (e-nose) technology is a type of…

multimodal Apache-2.0 Software Python ★ 9

AI-powered patient-to-clinical-trial matching using reasoning models for eligibility decisions.

text-generation in-development ★ 1
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llm-basics

Project

LLM Basics Simple, self-contained examples showing how to use an OpenAI-compatible API for various AI tasks. The scripts work with OpenAI directly or any other OpenAI-compatible endpoint (vLLM, LLM Factory,…

Software Python

Kentucky Open Science — wiki and task board This repository is two things: The KOS wiki at kentucky-open-science.github.io: a searchable page for every public repository in the Kentucky-Open-Science organization, generated…

Software JavaScript
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Quick Start: LLM Factory (OpenAI-compatible) This is a fork of Alishahryar1/free-claude-code, maintained by Evan Damron. It adds an openai_compatible provider that points FCC at any OpenAI-compatible Chat Completions endpoint —…

MIT Software Python ★ 1
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The Academic Foundation Model Index (AFMI) An index of foundation models trained natively, from scratch, on their own data and tokenizer, by academic and research institutions. Universities come first; research…

CC0-1.0 Software Ruby ★ 3

AI Models

Pre-trained and fine-tuned models for computer vision, NLP, and medical AI.

View all 21
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KOS-V5

Model

Variants: Kentucky-Open-Science/KOS-V5-Base, Kentucky-Open-Science/KOS-V5-Instruct license: apache-2.0 library_name: transformers pipeline_tag: text-generation language: en developed_by: University of Kentucky (College of Medicine Office for Research; Center for Clinical and Translational Science) and University of…

text-generation apache-2.0 Model family
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DALE-CT-2S

Model

image-feature-extraction cc-by-nc-sa-4.0 released

text-generation cc-by-nc-sa-4.0 released
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DALE-CT

Model

Variants: Kentucky-Open-Science/DALE-CT-1S, Kentucky-Open-Science/DALE-CT-2S, Kentucky-Open-Science/DALE-CT-0, Kentucky-Open-Science/DALE-CT-1S-v2 license: cc-by-nc-sa-4.0 datasets: ibrahimhamamci/CT-RATE rajpurkarlab/ReXGroundingCT library_name: timm pipeline_tag: image-feature-extraction tags: university-of-kentucky medical radiology chest-ct vision lejepa language: en Model Card for DALE-CT-1S Authors: Evan W.…

image-feature-extraction cc-by-nc-sa-4.0 Model family
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DALE-CT-0

Model

image-feature-extraction cc-by-nc-sa-4.0 released
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DALE-CT-0-L

Model

Model Card for DALE-CT-0-L Authors: Evan W. Damron (ORCID 0009-0009-1104-3202) · Mahmut S. Gokmen · Mitchell A. Klusty · Caroline N. Leach · Emily B. Collier · V. K. Cody…

image-feature-extraction cc-by-nc-sa-4.0 Model

Datasets

Curated datasets for training and evaluation.

View all 1
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TEMI-VOC

Dataset

Imported from hfds:Kentucky-Open-Science/TEMI-VOC. Source last updated 2026-08-12. Synced 2026-08-12.

apache-2.0 Dataset

Recent Publications

Peer-reviewed papers and preprints from Kentucky researchers.

View all 63

Abstract Nontuberculous mycobacteria (NTM) are ubiquitous bacteria that cause a spectrum of diseases, most notably pulmonary disease (NTMPD). The host factors contributing to the heightened susceptibility and severity of NTMPD…

2026 Research square

Abstract Alzheimer's disease neuropathological changes (ADNC)-operationalized with semi-quantitative parameters-represent the consensus-based gold standard for diagnostic evaluation of disease severity. Although useful, ADNC diagnostic frameworks have limitations, particularly in advanced disease…

2026 Brain pathology (Zurich,...

Abstract Coronary artery calcium (CAC) scoring is a key predictor of cardiovascular risk, but it relies on ECG-gated CT scans, restricting its use to specialized cardiac imaging settings. We introduce…

2026 arXiv preprint

Abstract Automated radiology report generation from 3D computed tomography (CT) volumes is challenging due to extreme sequence lengths, severe class imbalance, and the tendency of large language models (LLMs) to…

2026 arXiv preprint

Abstract Coronary artery disease (CAD), one of the leading causes of mortality worldwide, necessitates effective risk assessment strategies, with coronary artery calcium (CAC) scoring via computed tomography (CT) being a…

2026 Medical & biological...

Abstract Histopathological image analysis plays a critical role in modern medical diagnostics, particularly in the detection and classification of various types of cancer. This study proposes a method called HistoDARE…

2025 Scientific reports

Grants & Funding

Federal and institutional grants supporting Kentucky research.

View all 24

Agency: NIH/NIDAAward Number: 1U54DA058256-01Program: AppalTRuST Project 3

active NIH/NIDA

Agency: College of Medicine

inactive College of...

Agency: NSFAward Number: OCI-1246332

inactive NSF

Agency: NSFAward Number: CNS-1541380

inactive NSF

Agency: NIH/HHSAward Number: R01 DK124774

active NIH/HHS

Expanding access to AI training resources across Kentucky through the NAIRR pilot program.

active NSF (National...

Platform

Self-service tools for researchers — no programming expertise required.

View all 10
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Astral

Platform

The agent layer: an orchestrator plans each task and calls specialist agents, each exposing one capability through the Model Context Protocol, under the participant’s own delegated authority.

active
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Audio Foundry

Platform

Secure, web-based transcription platform with speaker labeling, timestamps, summarization, and theme extraction. Previously CAT-Talk.

automatic-speech-recognition active
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CLASSify

Platform

No-code web platform for training, comparing, and explaining classification and clustering models on tabular data, with synthetic data generation.

tabular-classification active
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Cresco

Platform

The transport layer: a distributed agent framework whose agents link isolated resources into one secure mesh and move data or computation under each site’s access controls.

active
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Forecaster

Platform

Web platform for time-series forecasting with multiple models and language-model-assisted interpretation, no programming required.

time-series-forecasting active
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GaiaKeep

Platform

The durable data layer: a sovereign, agent-focused storage platform that runs locally over Cresco and keeps datasets, models, and code as versioned, citable collections.

active